Upcoming & Archived Events
Webinar: Role of UDP-Glucuronosyltransferases in Drug Metabolism and Drug-Drug Interactions
The importance of glucuronidation for metabolism of xenobiotics in humans is illustrated by the abundance and broad tissue distribution of the enzymes, the diversity of…
Webinar: Underprediction of Drug Clearance by Aldehyde Oxidase (AO)–Mediated Drug Metabolism: Important Considerations for In Vitro Assessment
Aldehyde oxidase (AO) enzyme has gained increasing attention in drug development as one of the alternative approaches to reduce P450-mediated drug metabolism liability. However, clinical…
Webinar: Addressing Unique Challenges with Custom In Vitro Test Systems
Sometimes, standard products just don’t fit the objective of a unique assay. In this webinar, Products Director and custom test...
Webinar: The Role of In Vitro Assays in Selecting the Right Species for Your Small Molecule Program
Choosing the most relevant species for your toxicity studies is critical to ensure your IND provides the relevant data regulators need to advance your program…
Webinar: Red Blood Cell Partitioning Studies to Improve Accuracy in Pharmacokinetics (PK) Calculations
Pharmacokinetic (PK) parameters of a new drug candidate are typically determined by measuring the drug’s concentration in plasma. However, many drugs have the potential to…
Webinar: An Overview of Non CYP-Mediated Metabolism Pathways and In Vitro Evaluation Strategies
Although cytochrome P450 (CYP)-mediated metabolism continues to be of major importance for a large proportion of small molecule new drug candidates, various methods in recent…
March 31st DDI Guidance Webinar with Access to a Panel of Drug Metabolism & DDI Experts
Why should you follow DDI guidance even if you don’t have to? If you missed getting the answer to this question in November 2020 because…
2C or Not 2C: CYP2C Induction Studies for Successful Preclinical Risk Assessment
As a part of IND-enabling preclinical drug development studies companies are required to meet regulatory expectations to evaluate the induction...
DMDG Webinar – Comparison Between the Final FDA, EMA, and PMDA In Vitro DDI Guidance Documents: Are We Finally Harmonized?
Dr. Ogilvie offers his expert perspectives on major updates in the FDA’s Final Guidance for Industry and takes a magnifying glass to the differences between…
Presentation at 2020 ACT Meeting
At 3pm on Nov. 13, Drs. Andrew G. Taylor and Pallavi Limaye will present “In Vitro ADME and Drug-Drug Interaction...