Scientific Posters
Comparison of two hepatic uptake assay methods
Full Title “Comparison of two hepatic uptake assay methods, plated and oil layer methods, using human and preclinical species cryopreserved hepatocytes” Authors Akito Takahashi, Ryota...
Evaluation of interspecies metabolic activities for non-CYP enzymes
Presented at the 32nd Annual Meeting of Japanese Society for the Study of Xenobiotics (JSSX) in Tokyo, Japan Full Title “Evaluation of interspecies metabolic activities...
Further exploration into the DDI between Gemfibrozil & Repaglinide in rats: Uptake Transporters
Full Title Further exploration into the DDI between Gemfibrozil & Repaglinide in rats: Uptake Transporters Authors Chase I. McCoy, Forrest A. Stanley, Chandra Kollu, Seema...
Effects of organ preservation solution on aldehyde oxidase and xanthine oxidase activity in pooled human liver S9
Full Title Effects of organ preservation solution on aldehyde oxidase and xanthine oxidase activity in pooled human liver S9 Authors Kevin C. Lyon, Chad Pope,...
Characteristics of Fatty Liver Disease (FLD) Tissue Infographic
Full Title Characteristics of Fatty Liver Disease (FLD) Tissue Infographic Abstract Over 20+ years of pharmacokinetic studies, XenoTech has accumulated normal and diseased tissues representing...
Hepatocytes as the preferred test system to evaluate oligonucleotide-CYP Interactions in vitro
Full Title Hepatocytes as the preferred test system to evaluate oligonucleotide-CYP Interactions in vitro Abstract XenoTech previously examined the potential of oligonucleotides to inhibit cytochrome...
Research collection of variants of normal and fatty liver disease in human livers
Full Title Research collection of variants of normal and fatty liver disease in human livers Abstract XenoTech has developed a Research Biobank that is a...
Evaluation of the CYP metabolic activities in the presence of albumin in human liver microsomes
Full Title Evaluation of the CYP metabolic activities in the presence of albumin in human liver microsomes Abstract Cytochrome P450 (CYP) isoforms are responsible for...
Evaluation method for mitochondrial toxicity using Crabtree effect
Full Title Evaluation method for mitochondrial toxicity using Crabtree effect Abstract Mitochondria plays a crucial role in living organisms, one of which being the synthesis...
In Vitro Evaluation of Ketoconazole and its Alternatives as Non-CYP Inhibitors
Full Title The In Vitro Evaluation of Ketoconazole and its Alternative Clinical CYP3A4/5 Inhibitors (Ritonavir, Clarithromycin and Itraconazole) as Inhibitors of Non-CYP Enzymes Abstract Ketoconazole...