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ADME 101: Guide to Subcellular Fractions and When to Use Which Test System

  • Published on May 13, 2020
  • ADME 101™
  • Test Systems & Methods
  • Webinars

Presenter:  Chris Bohl, Ph.D., Global Technical Support Manager

This ADME 101 video provides an overview of different types of subcellular fractions, such as microsomes, S9, cytosol, lysosomes and homogenate, and their unique benefits for use in various types of vitro ADMET/DMPK & Drug-Drug Interaction studies. This short, information-packed webinar features:

  • The different types of subcellular fractions
  • How they are made
  • Who uses them, for which studies, and why
  • Advantages of the test systems
  • Different preparation options
  • Whether to use a NADPH regenerating system or 1mM NADPH
  • How tissue is procured and more…

About the presenter: Dr. Chris Bohl received his PhD from the School of Biological Sciences from the University of Nebraska – Lincoln and has been with SEKISUI XenoTech since 2014, first operating as a research scientist before becoming the Senior Manager of Technical Support for Products. Chris provides valuable guidance to scientists seeking to choose the correct test system, troubleshoot difficulties and much more.

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