Year: 2019
Cypex Adds Recombinant UGTs
- Updated Offerings
- September 3, 2019
- Madison Esely-Kohlman
Recombinant enzymes represent a useful test system for studies requiring extra high levels of catalytic activity. Due to high customer demand, Cypex has...
Consultancy Expansion
- Consultancy
- August 20, 2019
- Madison Esely-Kohlman
We are proud to house some of the brightest minds in this field who have seen “the weird stuff” when...
Can CYP3A4 Induction Predict P-glycoprotein Induction in DDI Studies?
- Enzyme Induction
- August 20, 2019
- Shanté Jackson, Madison Esely-Kohlman
Generally, a drug’s effects on enzyme and transporter activity are examined independently in a drug development program, but what if...
Reduced Pricing for In Vitro Transporter Studies
- Updated Offerings
- August 20, 2019
- Madison Esely-Kohlman
We’re pleased to announce that our scientists’ ongoing dedication to enhancing our processes and discovering new efficiencies without sacrificing quality...
XenoTech Named Best for Drug Candidate Evaluations 2019, Leading Providers of Pharmaceuticals Safety Testing
- Updated Offerings
- August 12, 2019
- Michael Millhollen
XenoTech has been named the Best for Drug Candidate Evaluations 2019 as well as in the Leading Providers of Pharmaceuticals...
In Vivo ADME: What You Need and Why You Need It
- In Vivo & Radiolabeling
- July 22, 2019
- Madison Esely-Kohlman, Satoshi Ito
When putting together a data package for regulatory approval by the FDA, EMA, or PMDA, there is a lot to...
The Story of Us
- Updated Offerings
- July 1, 2019
- Madison Esely-Kohlman, Satoshi Ito
This year at XenoTech we celebrate our 25th birthday, and our partner in Japan turns 64! Looking back over our history,...
Transporters of Emerging Importance in Drug Development: Beyond the Guidance Documents
- Regulatory Guidance
- June 25, 2019
- Madison Esely-Kohlman, Dr. Brian Ogilvie
Dr. Ogilvie’s presentation discusses critical literature and case studies which have been published following the FDA’s 2017 guidance revision, and covered...
Cell Handling & Media Selection for Best Results in Hepatocyte Assays
- Test Systems & Methods
- June 19, 2019
- Dr. Chris Bohl, Madison Esely-Kohlman
Getting reliable, reproducible results from studies using hepatocytes as a model system for drug metabolism is in part dependent on how well...
In Vitro Induction Studies: Elements of Design and Important Considerations in Data Analysis
- Enzyme Induction
- May 13, 2019
- Madison Esely-Kohlman, Dr. Joanna Barbara, Rebecca Campbell
Why do induction studies? Induction potential is an important piece of the drug-drug interaction (DDI) component of an IND submission. Simply put, we...
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