December 2019

What You Need to Know About Micro-Autoradiography (mARG) Distribution Studies

Author: Jolanta Golec, Madison Knapp Posted: 19 December 2019

In vivo determination of drug localization in tissue can be uniquely informative to drug developers investigating distribution within the context of the ADME/pharmacokinetic profile of their drug compounds. Micro-autoradiography can demonstrate sites of accumulation of a drug and drug-related material, which can be used as supplemental data for evaluation of parameters such as toxicity, efficacy, drug penetration, or differential metabolite distribution...

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