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Updated Look & Fresh Features: Welcome to Our Brand New Website!

For those of you who are used to coming to for news, updates, and fresh DDI/ADME content, you’ve probably noticed something is a little different today.

We are thrilled to welcome you to the brand new SEKISUI XenoTech website! The reconstruction project is a massive overhaul of over 1,000 pages carefully recrafted to reflect the needs and values of our customers and fellow researchers in the drug development community. We strive to respond to and integrate feedback about what kinds of information and resources are helpful to you, so it is with great pleasure that we introduce you to the revitalized portal into our expertise and expanse of offerings.

In addition to an updated look and feel, we have restructured and updated each page in our product and service sections to make it easy to find the information you’re looking for.

For those of you who are familiar with our old site and have come to appreciate the level of detail our scientists have historically provided for online materials—don’t worry, it’s still there! We’ve maximized the level of scientific detail on each page, now with improved organization for easier navigation, and added some features to improve your experience. Here’s a breakdown of what’s new and different:

Scientific Resources and Blog: Now explore your particular topics of interest

Access ADMETM is our remodeled scientific resource hub containing a wide variety of informational content sorted by topic. This area gives you access to all you might want to know in the world of ADME and DMPK. In sections such as Regulatory Guidance, Drug Metabolism, Biologics & Oligonucleotides, Drug Transporters, Enzyme Induction & Inhibition, In vivo / Radiolabeling, Non-CYP Enzymes, Test Systems & Methods, Drug-Drug Interactions, and Disease-State Resources, researchers and industry professionals can discover webinars, publications, scientific posters, and more to align with your area of interest. You can also find commentary on advances in the field, regulatory updates and expectations, and considerations to reduce or properly evaluate risk in our Drug Development Insights (DDI) blog.

How We Help

This new corner of the website paints a picture of how ADME testing fits into a drug’s development, and how our in vitro and in vivo studies, expert consultancy, and high-quality in vitro test systems can help drug developers come to their IND with data satisfying regulatory expectations. Over the last 25 years, we have grown from a small lab focused on drug-metabolizing enzymes to a global CRO that provides a wide variety of DMPK contract studies and test systems to help drug developers understand their compounds’ ADME and drug-drug interaction (DDI) potential. How We Help catalogues different questions drug developers have that we can help answer. We address questions like, “What nonclinical ADME and DDI studies do I need for a successful IND/NDA?” and “How can I mitigate my risk of late-stage failure?” Our mission is to give drug developers tools they need to bring safe therapeutics to market. Those tools are plentiful, and it’s important for our clients to see all the options they have available to help overcome their challenges.

Find It Now: Tools to search & compare lots and test system formats

If you come to our website looking for a particular product, or at least a product that fits some specific criteria, we have a place on the new site just for you. Find It Now lets you choose the combination of format, species, and gender for the test system you need and compare information between relevant lots or products so you can make an informed decision quickly and easily. In our comparison view, you can export tables to Excel that you could sort by pool size and enzyme activity and find the lots appropriate for your assays.

Streamlined contact process for requests, questions, feedback

It’s now easier than ever to get in touch. We’ve done away with special email addresses and phone numbers you need to hunt down to get a question answered (though you can still reach us that way if it’s saved in your contacts!). The process is streamlined now—with a simple form accessible from every page of the website, to quickly reach the right person for your query. Whether you have a question about a specific service or product we offer, need to get in touch with your region’s representative or distributor, would like to offer a webinar suggestion, or any other question or feedback, use the “How can we help?” tab on the right-hand side of the screen or Contact Us link at the top and bottom of the pages to fire off a message straight to the team. By including some basic information about your location, it lets you skip the triage step and go straight to the representative who’d be able to connect you with the product, service, or event you might need.

In vivo ADME services

XenoTech started as a purely in vitro drug metabolism study provider, and over the years we have grown to encompass many other services that relate to understanding risk related to metabolism, drug transport, and drug-drug interactions. Part of that growth has been our partnership with the Drug Development Solutions Center, which provides an in vivo complement to our in vitro expertise. Their experts have been building a reputation as the market-leading ADME provider in Japan, and now we enable a bridge for North American and European clients to gain access to their 50+ years of radiolabeling and in vivo ADME experience. Our partnership is seamless, providing clients with US-based liaisons to accompany you through each contracted study in vitro or otherwise, as reflected in our new website. In the Radiolabeling & In Vivo ADME/PK services section, you can find study design elements, features and benefits, and detailed information about the facility and accreditation. Jump into the meat-and-potato studies such as quantitative whole body autoradiography (QWBA), mass balance, radioisotope (RI) synthesis, and ‘hot’ compound metabolite ID, or explore more nuanced study options to help you answer questions about your drug’s distribution and disposition (like plasma protein binding, microautoradiography (mARG), or biliary excretion).

Get to know your Study Directors

There’s nothing quite like getting to put a face to the name of the person in charge of your drug safety study. You might have seen our Meet the Scientist series, where we sit down with some of our scientific experts at SEKISUI XenoTech. Now, you can use our site to get familiar with more of our most experienced study directors and seasoned scientists in the new Meet the Experts section. Meet Zell, who heads up our Products team and has been with SEKISUI XenoTech since 1996; or Lois, who leads the Enzyme Inhibition service group and is cited by the most recent FDA drug interaction guidance for industry; and a variety of other SEKISUI XenoTech scientists! Our greatest asset is the strength of our team, so we welcome you to have a peek behind the curtain and meet the people behind the data.

Come explore! Check out our new dynamic and interactive homepage; take a look at the refreshed About section to re-introduce our values and direction. If you have questions or feedback, be sure to test out the new Contact Us box—we look forward to hearing from you!

– Your SEKISUI XenoTech Team

About the Authors

Madison (Knapp) Esely-Kohlman received her BS from the University of Missouri – Columbia and is currently SEKISUI XenoTech’s Marketing Communication Specialist, developing scientific content that communicates the value and expertise of internal contract service and test system production teams. Madison joined SEKISUI XenoTech as the Scientific Communications Coordinator in 2019 after serving in similar positions at CropLife America, Bond Life Sciences Center and the University of Missouri CAFNR Office of Communications.

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