Company

Sekisui XenoTech’s mission is to lead collaborations with the world’s principal researchers and scientific experts, advancing life-enhancing therapies with unparalleled insight and interpretation through high value products and bespoke services.

Our vision is to be the world's foremost facilitator in the pursuit of life-enhancing therapies.

About Sekisui XenoTech

Sekisui XenoTech was founded to provide scientists and pharmaceutical researchers with the finest tools and resources needed to advance the development of safer drugs. We employ strict quality standards following well-developed and time-tested standard operating procedures to ensure the highest level of performance, saving you valuable time and money. It's through this unwavering dedication to sound science that we make sure our work is done right - the first time. At Sekisui XenoTech, we are committed to satisfying not just your company's needs, but also the expectations of the FDA or any global regulatory agency that might review our reports and scientific opinions.

Our wealth of experience and expertise, our understanding of the latest regulatory guidance and industry whitepapers and our commitment to research and development has made Sekisui XenoTech a trusted partner and expert consultant to 35 of the top 40 pharmaceutical companies worldwide, as well as numerous biotech, small, medium and virtual pharma.

Sekisui XenoTech's strong reputation for high quality in vitro drug metabolism studies attracted the attention of Sekisui, who became our parent company in August, 2008. This alignment has allowed us to offer a much wider range of services to accelerate drug development, including the areas of in vivo ADME, Drug Metabolism, Transporters and Drug-Drug Interactions.

Sekisui XenoTech is a premier provider of in vitro drug metabolism and drug-drug interaction studies to pharmaceutical companies worldwide. We have unparalleled experience in evaluating drug candidates as substrates, inhibitors and inducers of drug-metabolizing enzymes. Core capabilities include Enzyme Inhibition, Enzyme Induction, Drug Metabolism, Drug Transport and Analytical Services.

Sekisui XenoTech's Core Capabilities:
  • CYP Enzyme Inhibition
  • UGT Enzyme Inhibition
  • Inhibition Express (screening)
  • In vitro Enzyme Induction
  • Ex vivo Enzyme Induction
  • Drug Transporters
  • Reaction Phenotyping
  • Metabolite ID
  • Species Comparison
  • Metabolic Stability
  • Covalent Binding
  • Protein Binding
  • Toxicology
  • Anaytical Services (Bioanalysis)
  • Biologics
  • Consulting

Expanded offerings through Sekisui:

In vivo ADME
  • Drug plasma concentration
  • Absorption site investigation
  • Tissue distributions
  • QWBA (Quantitative Whole Body Autoradiography)
  • Plasma protein binding
  • Blood/plasma partition rate
  • Lymphatic partition rate
  • Metabolic profile (plasma, urine, bile and tissue)
  • Metabolite Identification
  • Excretion rate (urine, feces, expiration air and bile)
  • Enterohepatic circulation
  • Radiolabeled Synthesis
  • Bioanalysis by ECL

 
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