HepatoSure® Pooled Human Hepatocytes

Current Promotions


HepatoSure® is SEKISUI XenoTech’s 100-donor pool of cryopreserved human hepatocytes for suspension. As the largest pool that Sekisui XenoTech offers as a standard product, HepatoSure® provides the best value when it comes to consistency of data reproducibility. We strongly recommend utilizing our K8500 OptiThaw Hepatocyte kit with all HepatoSure® cells, a nutrient rich media which ensures consistent cell yield and the highest possible viability.

SEKISUI XenoTech offers two different cryopreserved pooled human hepatocyte products, HepatoSure® and CryostaX®, and has the widest variety of human hepatocyte products on the market.

Characterization Provided

Enzyme Marker Substrate Reaction
CYP1A2 Phenacetin O-dealkylation
CYP2A6 Coumarin 7-hydroxylation
CYP2B6 Bupropion hydroxylation
CYP2C8 Amodiaquine N-dealkylation
CYP2C9 Diclofenac 4'-hydroxylation
CYP2C19 S-Mephenytoin 4'-hydroxylation
CYP2D6 Dextromethorphan O-demethylation
CYP2E1 Chlorzoxazone 6-hydroxylation
CYP3A4/5 Testosterone 6β-hydroxylation
CYP3A4/5 Midazolam 1' -hydroxylation
UGT 7-Hydroxycoumarin glucuronidation
SULT 7-Hydroxycoumarin sulfonation
AO p-Vanillin
AO Phthalazine
OCT1 1-Methyl-4-phenylpyridinium iodine
OATP1B1 Esterone sulfate
OATP1B3 Cholecystokinin-8
NTCP Taurocholic acid
*Includes intrinsic clearance for CYP1A2, 2C8, 2C9, 2D6 and 3A4/5

Features and Benefits of HepatoSure®

  • 100 donors reducing inter-individual variability
  • Large donor pool size reduces lot-to-lot variability
  • Large lot sizes
  • Most extensive characterization on the market; includes transporter activities, AO activity and intrinsic clearance values
  • High viability and enzyme activity levels
  • Maintains strong viability for up to 4 hours

View SEKISUI XenoTech's cryopreserved hepatocyte thawing protocol here.
  Buy cell and tissue based products
Product Description Volume AMY
HCP100.H15 HepatoSure Cryopreserved Human Hepatocytes - 100 Donors - AMY 5 mil. 1mL 5 million
Find the Cellular Products You Need  
Can't find what you need? Have a question?
 Security code
(please note: pressing Enter will submit the form)
Or Call 1-877-588-7530
(+1.913.438.7450 If Outside North America)