Liver Disease Tissue Microarrays

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Tissue microarrays (TMA) are tools to study disease biomarkers in well-defined patient populations. Sekisui XenoTech supports basic research into fatty liver disease, a condition that has very significant impact on the health of modern society. We developed liver tissue microarrays for analysis of the progression of fatty liver disease in non-alcoholic steatohepatitis (NASH) and alcoholic steatohepatitis subjects.
 
We offer tissue arrays focused on:

The placement of targeted disease tissues and appropriate controls in the same arrays facilitates comparative analysis of biomarker distribution. Tissue donors’ data, including BMI and macrovesicular fat content, accompany the arrays. Our arrays are built with Research Biobank tissues, which were collected and preserved with the initial intent for human transplantation. The tissues are mounted on a typical microscope slide and are not stained or covered/overlaid. The microarrays are cut in small batches and stored at 4° under nitrogen.

The images below of hematoxylin/eosin and Masson’s trichrome-stained arrays illustrate histology and fibrosis on 3 mm diameter cores.
 
H&E Masson’s trichrome
Liver-Disease-Tissue-Microarray-H-E-Stained-Slide.gif Liver-Disease-Tissue-Array-Massons-Trichrome-Slide.gif

Array images are available in the datasheets on the product ordering pages below...
Buy cell and tissue based products
Product Description Amount
TMA.NASH Tissue Microarray- No Alcohol Steatohepatitis Each
TMA.ASH Tissue Microarray- Alcohol Steatohepatitis Each
TMA.NAS Tissue Microarray- No Alcohol Steatosis Each
TMA.AS Tissue Microarray- Alcohol Steatosis Each
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