Minipig Subcellular Fractions

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Liver subcellular fractions from toxicologically relevant animals provide a cost efficient and highly effective test system for in vitro studies of xenobiotic metabolism. Sekisui XenoTech’s animal subcellular fractions are pooled to yield activity levels representative of in vivo populations and are produced in large lots to ensure long-term product availability.

Many drug metabolizing enzymes of the liver are also expressed in the skin. While skin possesses a wide variety of metabolic enzymes, specific enzymatic activity is typically less than 10% of that found in the liver. However, skin plays a significant role in the biotransformation of transdermal xenobiotics. Sekisui XenoTech’s pooled minipig skin S9 fractions are most commonly used for in vitro ADME studies.

Sekisui XenoTech offers matching S9, cytosol and microsomal minipig fractions derived from Gottingen, Sinclair and Yucatan minipig liver and skin tissue. If you require minipig subcellular fractions not included in our standard product offering, custom products can be ordered to meet the needs of any study.

Features and Benefits:
  • Large donor pools minimize lot-to-lot variation
  • Large lots ensure long-term product availability
  • Unique preparation procedures allow for the production of matching S9, cytosol and microsome donor pools

Related Products:
Contact a Product Specialist for more information on Sekisui XenoTech’s subcellular fraction product offerings.
  Buy cell and tissue based products
Product Description Volume Protein Concentration
Z2000 Pooled Sinclair mini-pig liver microsomes, male, 20mg/mL 0.5mL 20 mg/mL
Z2000.S9 Pooled Sinclair mini-pig liver S9 fraction, male, 20 mg/mL 0.5mL 20 mg/mL
Z3000 Pooled Yucatan minipig liver microsomes, male, 20mg/mL 0.5mL 20 mg/mL
Z3000.S9 Pooled Yucatan mini-pig liver S9 fraction, male, 20 mg/mL 0.5mL 20 mg/mL
Z6000 Pooled Gottingen minipig liver micro- somes, male, 20mg/mL 0.5mL 20 mg/mL
Z6000.S9 Pooled Gottinen mini-pig liver S9, male, 20 mg/mL, 1mL vial 1mL 20 mg/mL
Z0610.ES9 Pooled Gottingen Minipig skin S9, mixed, 4mg/mL 0.5mL 4 mg/mL
Z6000.C Pooled Gottingen minipig liver Cytosol male, 10mg/mL 1mL 10 mg/mL
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