Human Liver Cytosol

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Human liver cytosol contains a wide variety of drug metabolizing enzymes and is commonly used to support in vitro ADME (Absorption, Distribution, Metabolism and Excretion) studies, especially when studying non-CYP enzymes.

Sekisui XenoTech features four different human liver cytosol products with matching microsomal and S9 fraction donor pools.
  • XTreme 200 Pooled Human Liver Cytosol
  • 50-Donor Mixed Gender Human Liver Cytosol
  • 10-Donor Male Human Liver Cytosol
  • 10-Donor Female Human Liver Cytosol
New! Sekisui XenoTech also offers donor pools that have been prepared to preserve high AO (aldehyde oxidase) and XO (xanthine oxidase) activity without significantly impacting major CYP activity (view poster), usually with matching S9 and cytosol pools.

Human Liver Cytosol Test System Features and Benefits:
  • Matching microsomes, S9 and cytosol for most donor pools
  • Large donor pools minimize lot-to-lot variation and increase the long-term availability of each lot
  • Each donor is significantly represented in the final pooled product
  • Extensively characterized using validated LC-MS/MS methods
Related Products:  
Custom human liver cytosol can be prepared if your study has specific donor requirements. For more information on human liver cytosol, download our subcellular fraction flyer or contact a Sekisui XenoTech Product Specialist today.
  Buy cell and tissue based products
Product Description Pool Size Volume
H0606.C(AX) Mixed Gender Human Liver Cytosol - High AO/XO Activity, Pool of 20 20 1mL
H0610.C Pooled human liver cytosol, mixed gender 1mL @ 10mg/mL 50 1mL
H1000.C Male Human Liver Cytosol - 1mL @ 10mg/mL 10 1mL
H1500.C Female Human Liver Cytosol - 1mL @ 10mg/mL 10 1mL
H2610.C XTreme 200 Mixed Gender Human Liver Cytosol, 1mL @ 10mg/mL 200 1mL
*Cytosol fractions are supplied at a concentration of 10 mg/mL in 50 mM TRIS•HCI, (pH 7.4 at 4°C) containing 150 mM KCl and 2 mM EDTA.
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