Hepatocytes are commonly used in drug discovery and preclinical development to conduct in vitro studies investigating metabolism, clearance, uptake, hepatotoxicity, cell biology, drug-drug interaction.
Discounted Hepatocytes for In Vitro DMPK Assays in Drug Development
Use promo code “CLEARANCE” to save 40% off* any of the lots on the following pages:
Intact hepatocytes contain the major hepatic drug-metabolizing enzymes required to study the four categories of xenobiotic biotransformation: hydrolysis, reduction, oxidation and conjugation. Because of these enzymes, hepatocytes provide a viable and cost-effective alternative to in vivo testing.
As the industry leader in tissue-derived products for drug metabolism studies, we offer the widest variety of human and animal hepatocyte test systems, representative of many key preclinical animal species and human hepatocyte pool sizes ranging from individual donors to HepatoSure®, our 100-donor human hepatocyte pool for predictive enzyme activity levels and minimized effects of donor-to-donor variability.
Thawing & Plating Cryopreserved Hepatocytes:
Check out the following demos to learn proper thawing and plating procedures for any of our cryopreserved human or animal hepatocytes: