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CryostaX Pellets: Improving hepatocyte pooling, activity and lab efficiency

  • Published on September 27, 2018
  • Test Systems & Methods
  • Webinars

Presenter:  Chris Bohl, Ph.D., Global Technical Support Manager

Synopsis:
CryostaX® hepatocytes are created using a patented process that produces unique single-donor cell pellets. This format allows for distinct benefits to hepatocyte performance, efficiency in the lab, and test system design, precipitating the potential discontinuation of cryopreserved hepatocytes prepared from traditional methods. This webinar will discuss the technology, its optimal utilization and benefits…Key concepts discussed in this webinar will include:
  • How single-freeze hepatocyte pellets preserve higher metabolic activity, longer
  • The benefits of skipping the thaw step
  • Pellet pooling versatility (demographics for human pools; larger rodent lot sizes)
  • Patented cryopreservation technology overview

About CryostaX:
CryostaX® patented hepatocyte technology makes using cryopreserved hepatocytes easier, more robust, and more efficient. Easier because you no longer need to thaw the vial of hepatocytes in a traditional water bath. Simply pour loose pellets into the thawing medium and spin. Higher metabolic activity pools because CryostaX technology allow the creation of fully customizable pools that have undergone only a single cryopreservation step, leading to less cryoinjury. More efficiency in the hood/bench because hepatocyte thaw variability is decreased and you are able to customize pools with specific demographics for your work. CryostaX hepatocytes come in all commonly used hepatocyte formats, are customizable (at no additional cost) for assured minimal yield per individual donor vial, and feature fast turnaround (in your hands in approx. 3-4 business days).

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