In Vitro Evaluation of Immunomodulating Drugs as Perpetrators of Drug Interactions

In Vitro Evaluation of Immunomodulating Drugs as Perpetrators of Drug Interactions

Aired:  2/20/2019 1:00:00 PM

Presenter: Dr. Maciej Czerwinski, Sekisui XenoTech Director of Consulting

Synopsis:
On October 15th, 2018, Sekisui XenoTech presented on "In Vitro Direct and Cytokine-Mediated Effects of Therapeutic Peptides and other Biologics on CYP Enzymes" at the Peptide ADME Discussion Group Workshop in Gothenburg, Sweden. Following subsequent requests for a follow-up webinar, Dr. Czerwinski will be presenting on the following subjects...

Key concepts discussed in this webinar will include:
  • Immunomodulators
  • Mechanisms of immunomodulator drug-drug interactions (DDI)
  • Regulatory guidance on evaluating DDI potential of biologics
  • Study design to evaluate direct and cytokine-mediated effects of immunomodulators on drug metabolizing enzymes
  • Case studies of experiments conducted according to our study design...

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