cryostax-vials.jpgSekisui XenoTech offers unrivaled quality and selection with an extensive array of products to assist all your in vitro ADME research needs. Our standard products feature cellular and subcellular fractions, hepatocytestissue samples, media and more from many different toxicologically relevant species. We are the sole North American distributor for cell lines from JCRB, recombinant CYP enzymes, P450 substrates and metabolites from Cypex, and metabolite production kits from HepatoChem. Whatever your in vitro research needs, Sekisui XenoTech can help. Order all your products online in our eStore!

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Sekisui XenoTech's scientific resources as well as cell and tissue-based products stem from our unparalleled global contract research experience and proven expertise from discovery through clinical support.

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News and Events

  • Wednesday, February 01, 2017

    Sekisui XenoTech Adds New Dermal Subcellular Fraction Test Systems

    Sekisui XenoTech is adding human and minipig to the company’s list of species with dermal subcellular fractions available as standard test systems for the development of safer new products. Subcellular fractions are widely used in drug discovery and preclinical drug development to evaluate the in vitro metabolism of new therapeutics.

  • Wednesday, October 05, 2016

    Sekisui XenoTech Introduces Lysosomal Test Systems for Biopharmaceutical Development

    Hepatic human lysosomes and rat tritosomes are now available as standard test systems. These products contain high concentrations of lysosomal degradative enzymes and constitute advantageous test systems for analysis of catabolism and/or activation for targeted biopharmaceuticals that enter cells through the endosomal-lysosomal pathway...

  • Tuesday, April 12, 2016

    XenoTech Provides Genotyped Hepatocytes for Polymorphic Enzyme Drug Metabolism Studies

    Geneknown™ hepatocytes are genotyped cryopreserved human hepatocytes pooled to study the effects of specific genetic variants on drug metabolism and transport to identify risks of adverse drug interactions present only in genetically-defined subpopulations of patients. Genetically determined transport and metabolism polymorphisms have been recognized by the FDA as having potential safety and efficacy implications. This is particularly important for poor metabolizers in cases of drugs metabolized predominantly by polymorphically expressed enzymes.