

Test Systems & Methods
Drug-Drug Interaction (DDI) Prediction Models Following In Vitro Studies in Preclinical Development
- Drug Drug Interactions (DDI)
- August 12, 2020
- Madison Knapp, Dr. Pallavi Limaye, Andrea Wolff, Dr. Maciej Czerwinski
In preclinical development, a drug will be evaluated for potential to cause a drug-drug interaction (DDI) using in vitro experiments and then calculations that...
Toxicokinetic (TK) Analysis for Preclinical Drug Development
- In Vivo & Radiolabeling
- August 6, 2020
- Madison Knapp, Jolanta Golec, Dr. Pallavi Limaye
The main goal of preclinical toxicokinetic (TK) studies is to establish a correlation between a candidate compound’s concentration or dose...
New TMPRSS2-Expressing Cell Line for COVID-19 Research
- Updated Offerings
- April 23, 2020
- Madison Knapp
We are offering a brand new cell line to assist researchers in the fight against COVID-19.The cell line (JCRB1819), developed...
What is ADME and how does it fit into drug development?
- Test Systems & Methods
- April 10, 2020
- Madison Knapp, Dr. Brian Ogilvie
The main aim of drug development is to get a compound that has a therapeutic effect into the form of...
How to Choose the Right Test Systems for Your DMPK Studies
- Test Systems & Methods
- September 12, 2019
- Dr. Chris Bohl, Madison Knapp
Test systems for DMPK in vitro studies are part of the very foundation of our company. Our labs were borne of...
Cypex Adds Recombinant UGTs
- Updated Offerings
- September 3, 2019
- Madison Knapp
Recombinant enzymes represent a useful test system for studies requiring extra high levels of catalytic activity. Due to high customer demand, Cypex has...
Cell Handling & Media Selection for Best Results in Hepatocyte Assays
- Test Systems & Methods
- June 19, 2019
- Dr. Chris Bohl, Madison Knapp
Getting reliable, reproducible results from studies using hepatocytes as a model system for drug metabolism is in part dependent on how well...
Quality Control is What Makes the Comprehensive Collection of Cell Lines from JCRB Among the Highest Regarded and Most Widely Distributed in the World
- Test Systems & Methods
- April 23, 2019
- Madison Knapp, Dr. Arihiro Kohara, Kimiho Yamada
About JCRB cell bank In addition to focus on preclinical ADME in vitro testing services and complementary products, SEKISUI XenoTech offers to our...
Minding Your Binding: Plasma Protein Binding Potential Study Now Available at Our US and Japan Labs
- Test Systems & Methods
- April 15, 2019
- Madison Knapp, Andrea Wolff, Dr. Joanna Barbara
While liver and intestine are important in ADME, behavior in blood is also crucial. When an orally administered drug or...
Disease-State Test Systems
- Test Systems & Methods
- January 13, 2019
- Michael Millhollen, Dr. Chris Bohl
SEKISUI XenoTech has been working with and supplying reagents for the pre-clinical ADME field for well over two decades. Years...
Subscribe to our Newsletter
Stay up to date with our news, events and research

Do you have a question or a request for upcoming blog content?
We love to get your feedback
