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test systems

Custom In Vitro Test Systems for DMPK Studies

Sometimes standard offerings don’t quite fit your needs– our dedicated Custom Products team is equipped with extensive experience with specialized isolation techniques and access to a wide array of species & tissue to provide our customers with the perfect test systems for their drug development assays. Use our Custom Preparations Request form to let us know what you need or check out our extensive selection of custom surplus inventory for non-standard products we have readily available.

  • Custom pooling of human hepatocytes specific to donor demographics, enzyme or transporter characterization, disease state, etc.
  • Fresh animal hepatocytes
  • Animal hepatic & extrahepatic subcellular fractions
  • Human hepatic & extrahepatic subcellular fractions
  • Individual human subcellular fractions (e.g., poor/extensive metabolizers, age, race, and other demographic specifications)
  • Customized human liver microsome pools (e.g., activity)
  • Pre-lysate, whole tissue samples
  • Fraction preparation from customer-provided tissue
  • Fraction preparation with custom buffers or protocols
  • Unparalleled experience developing specialized techniques to develop dependable preparations yielding quality data
  • Dedicated department for custom preparations, building expertise in working with difficult or delicate tissue
  • Over 40 characterization assays available
  • No minimum setup fee
  • Validated LC-MS/MS characterization methods by our designated Bioanalytical Services specialists
  • Specially tailored preparation methods

Custom Pooling for Human Hepatocytes

We can meet your needs with custom plateable or suspension hepatocyte pools, with individual donors selected for specific enzyme activity, assured minimum yield (AMY), BMI, disease state, age, ethnicity, gender, alcohol/drug/tobacco use, serologies, or other characteristics.

Animal Test Systems: Expansive Species, Tissue, and Fraction Options

SEKISUI XenoTech features custom preparations for hepatocytes and subcellular fractions. Below is a sampling of the species and tissue we’ve worked with in the past.

  • African Green monkey
  • B6C3F1 mouse
  • B6SJLF1 mouse
  • Balb/c mouse
  • Beagle dog
  • Brown Norway rat
  • C57BL/6 mouse
  • C57BL/6J mouse
  • Cat
  • CD-1 mouse
  • Chicken
  • Cow
  • Cynomolgus monkey
  • Db/db Lean mouse
  • Db/db Obese mouse
  • Fischer 344
  • Fox Chase SCID mouse
  • FVB mouse
  • GK rat
  • Goat
  • Golden Syrian hamster
  • Gottingen minipig
  • Hanford minipig
  • Hartley guinea pig
  • Horse
  • Human (many demographics)
  • Japanese White rabbit
  • KK.Cg-Ay/J mouse
  • KK/H1J mouse
  • Lewis rat
  • Long-Evans rat
  • Marmoset monkey
  • Mongolian gerbil
  • New Zealand rabbit
  • NU/NU nude mouse
  • Ob/ob Lean mouse
  • Ob/ob Obese mouse
  • Owl monkey
  • Pig (standard)
  • Rhesus monkey
  • SCID mouse
  • Sheep
  • Swiss Webster mouse
  • Trout
  • Wistar Han rat
  • Yucatan minipig
  • ZDF Lean rat
  • ZDF Obese rat

  • Adrenal gland
  • Bladder
  • Blood plasma
  • Brain
  • Colon
  • Duodenum
  • Eye
  • Heart
  • Ileum
  • Insect abdomen
  • Jejunum
  • Kidney
  • Liver
  • Lung
  • Muscle
  • Ovary
  • Pancreas
  • Skin
  • Spleen
  • Stomach
  • Testicle

  • Cytosol
  • Hepatocytes
  • Homogenate
  • Kupffer cells/Non parenchymal cells
  • Lysosomes / Tritosomes
  • Mast cells
  • Microsomes
  • Mitochondria
  • Pre-lysate
  • S9 fraction
  • Urothelial cells

Custom Preparation Surplus

Our Products Team regularly processes animal and human donor tissue. Our expertise and unique cell preparation procedures allow us to get the most out of each and every tissue. As a result, we often have surplus inventory of products remaining from our custom cell preparations.

Or Tell Us What You Need

With us, you have plenty of test system options. If we don’t already have it, we can likely make it for you. Use our simple Custom Request form to let us know just what you’re looking for and we’ll have one of our specialists get in touch with you shortly about getting your test system prepared as soon as possible.

See our capabilities

Find complete list of characterization assays, quality assurance details, typical timeline for preparations, and more

Cellular tissue sample in vitro assay

What’s available now?

Find a complete, updated list of all custom surplus inventory available for purchase immediately

Laboratory microsome S9 cytosol preparation