We know just how important your compound is to you and how critical it is to choose the right tools to carry it through the development pipeline. We also know ADME and drug-drug interactions; it’s what our scientists do all day every day. Let us help you find the right test systems for your in-house in vitro preclinical work.
In Vitro Test Systems & ADME / DMPK / DDI Studies
The success of a compound’s entry to Clinical Phase hinges on the quality of data. You can trust the quality of our products because they are used in our lab every day by our own research scientists for the same studies you perform. Together, we have invested over 25 years in developing and refining the tools you need to generate consistent, reliable data.
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Our In Vitro Products for Preclinical Testing
All human tissues accepted by Sekisui XenoTech have been tested for the possible presence of various infectious diseases, and SEKISUI XenoTech does not accept human-derived material unless the donor has tested negative (non-reactive) for RPR (rapid plasma reagent), HIVAb (human immunodeficiency virus antibody), HBsAg (hepatitis B surface antigen), HCVAb (hepatitis C virus antibody), and SARS-CoV-2 (as of March 2020).
All human tissue is also tested for CMVAb (cytomegalovirus antibody). However, due to the widespread (nearly ubiquitous) appearance of CMV in the population, and its relative insignificance as an infectious agent, tissues from donors reactive for CMVAb are accepted. The serology status of each donor is typically determined by ELISA or Nucleic Acid Test by the organ procurement hospital.
Not sure which test systems are best suited for studies?
We’ve got you covered. Use the links below to find a guide tailored to what kind of information you’re looking for; for a Quick Read, see our blog post providing an overview of our product offerings with key considerations for selecting formats that match your assay needs. Our Deep Dive is a downloadable PDF of our full Test Systems & Reagents Product Catalog with detailed appendices to provide technical isolation and application information for each product we offer.