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In Vivo & Radiolabeling

In vivo and radiolabeled compound studies are necessary for distribution data, dosing calculations for first in-human studies, bridging in vitro PK and toxicology data, and much more. Find resources here relating to our in vivo and radiolabeling services offered byt the Drug Development Soluctions Center. The Center offers GLP and non-GLP animal studies to investigate your drug’s pharmacokinetics as well as top-tier radioisotope (RI) compound labeling services for pharmaceuticals. For more information about these services, visit our In Vivo ADME/PK page.



The Role of In Vitro Assays in Selecting the Right Species for Your Small Molecule Program

Presenters: Andrew G. Taylor, Ph.D., Manager of Technical Support for Services at SEKISUI XenoTech and Scott Boley, Ph.D., DABT, Senior Vice President of Research at Sinclair...

Toxicokinetic (TK) Analysis for Preclinical Drug Development

The main goal of preclinical toxicokinetic (TK) studies is to establish a correlation between a candidate compound’s concentration or dose...


Missing Out on Annual ‘Comforting of the Soul’

As we begin this summer, many of us are grieving opportunities lost for parties and pool days with friends and...


What You Need to Know About Micro-Autoradiography (mARG) Distribution Studies

In vivo determination of drug localization in tissue can be uniquely informative to drug developers investigating distribution within the context of...


DDSC In Vivo ADME Expertise Providing Cost Savings

ADME studies are a vital part of the drug development process, and therefore, deciding where and how to perform these studies...


Mass Balance Studies: What You Need and Why You Need It

In vivo mass balance studies are an important element of nonclinical drug development, to inform first in-human (FIH) studies and to...


Why You Need QWBA for Human Radiolabeled ADME Studies

A quantitative whole body autoradiography (QWBA) study provides data required for Human Radiolabeled ADME Studies1. Quantitative whole body autoradiography (QWBA) is an in...


In Vivo ADME: What You Need and Why You Need It

When putting together a data package for regulatory approval by the FDA, EMA, or PMDA, there is a lot to...


The Story of Us

This year at SEKISUI XenoTech we celebrate our 25th birthday, and our Japan branch turns 64! Looking back over our history,...


Studies in Japan: Easier & More Beneficial than You Might Think

SEKISUI XenoTech is well-known to pharmaceutical companies and toxicology academics alike for unparalleled experience in quality in vitro ADME/DMPK/DDI studies and complementary...


To GLP or not to GLP?

That is the question. . . Knowing the answer may save you time and money Good Laboratory Practices (GLP) are...

Scientific Posters

MALDI-Imaging quantitation of neurotransmitters in rat brain using “Triple Spray” method

MALDI-Imaging quantitation of neurotransmitters in rat brain using “Triple Spray” method Presented at the 33rd JSSX Annual Meeting / 2018 MDO Meeting in Japan Toshimasa...

Choosing a Relevant Small Animal Model for Pharmacokinetic or Toxicity Studies

Choosing the most suitable small animal model is crucial for pharmacokinetic and/or toxicology studies in order to get usable, relevant data. Due to potential...

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