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In Vivo & Radiolabeling

In vivo and radiolabeled compound studies are necessary for distribution data, dosing calculations for first in-human studies, bridging in vitro PK and toxicology data, and much more. For more information about these services, visit our In Vivo ADME/PK page.

 

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Toxicokinetic (TK) Analysis for Preclinical Drug Development

The main goal of preclinical toxicokinetic (TK) studies is to establish a correlation between a candidate compound’s concentration or dose...

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Missing Out on Annual ‘Comforting of the Soul’

As we begin this summer, many of us are grieving opportunities lost for parties and pool days with friends and...

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What You Need to Know About Micro-Autoradiography (mARG) Distribution Studies

In vivo determination of drug localization in tissue can be uniquely informative to drug developers investigating distribution within the context of...

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In Vivo ADME Expertise Providing Cost Savings

ADME studies are a vital part of the drug development process, and therefore, deciding where and how to perform these studies...

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Mass Balance Studies: What You Need and Why You Need It

In vivo mass balance studies are an important element of nonclinical drug development, to inform first in-human (FIH) studies and to...

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Why You Need QWBA for Human Radiolabeled ADME Studies

A quantitative whole body autoradiography (QWBA) study provides data required for Human Radiolabeled ADME Studies1. Quantitative whole body autoradiography (QWBA) is an in...

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In Vivo ADME: What You Need and Why You Need It

When putting together a data package for regulatory approval by the FDA, EMA, or PMDA, there is a lot to...

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The Story of Us

This year at SEKISUI XenoTech we celebrate our 25th birthday, and our Japan branch turns 64! Looking back over our history,...

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Studies in Japan: Easier & More Beneficial than You Might Think

SEKISUI XenoTech is well-known to pharmaceutical companies and toxicology academics alike for unparalleled experience in quality in vitro ADME/DMPK/DDI studies and complementary...

Scientific Posters

MALDI-Imaging quantitation of neurotransmitters in rat brain using “Triple Spray” method

MALDI-Imaging quantitation of neurotransmitters in rat brain using “Triple Spray” method Presented at the 33rd JSSX Annual Meeting / 2018 MDO Meeting in Japan Toshimasa...
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Choosing a Relevant Small Animal Model for Pharmacokinetic or Toxicity Studies

Choosing the most suitable small animal model is crucial for pharmacokinetic and/or toxicology studies in order to get usable, relevant data. Due to potential...