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Year: 2019

What You Need to Know About Micro-Autoradiography (mARG) Distribution Studies

In vivo determination of drug localization in tissue can be uniquely informative to drug developers investigating distribution within the context of...

What In Vitro Metabolism and DDI Studies Do I Actually Need?

Though there is no ‘roadmap’ spelling out required studies to achieve regulatory approval for clinical entry, a drug candidate’s metabolism...

In Vivo ADME Expertise Providing Cost Savings

ADME studies are a vital part of the drug development process, and therefore, deciding where and how to perform these studies...

Mass Balance Studies: What You Need and Why You Need It

In vivo mass balance studies are an important element of nonclinical drug development, to inform first in-human (FIH) studies and to...

Meet the Scientist: Rachel Murphy, PhD

We thought it might be nice to put faces to the names of some of the scientists you interact with...

I Have My Data… Now What?

As a drug moves through the development pipeline, it undergoes a rigorous battery of safety assessments to prove it will...

The FDA has requested follow-up data… how do I fill in the gaps?

Because each new drug is unique in characteristics, such as chemical structure, mechanism of action, and physicochemical properties, there can...

Why You Need QWBA for Human Radiolabeled ADME Studies

A quantitative whole body autoradiography (QWBA) study provides data required for Human Radiolabeled ADME Studies1. Quantitative whole body autoradiography (QWBA) is an in...

SEKISUI XenoTech Named Best In Vitro Drug CRO 2019

SEKISUI XenoTech has been named the Best In Vitro Drug CRO in the 2019 Healthcare & Pharmaceutical Awards. From the...

How to Choose the Right Test Systems for Your DMPK Studies

Test systems for DMPK in vitro studies are part of the very foundation of our company. Our labs were borne of...

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Human antibodies, including monoclonal and polyclonal, are used for inhibition and immunoblot applications