Commentary to provide context and explain significance of research is sometimes just as important as the research itself. That’s why our experts make it a priority to provide you with helpful content distilled from the many years of experience our team has accumulated. The Drug Development Insights blog contains overviews and deep dives into the drug metabolism and pharmacokinetics topics you care about—regulatory expectations, risk assessment, safety considerations, scientific innovation, study design elements, interpretation of results, and more. Explore our entries chronologically or by category to get insight into the many pieces of your drug’s development.
Drug Development Blog
In Vitro DDI Regulatory Guidance Reference Poster
At the 2018 Marbach Castle Drug-Drug Interaction Workshop in Germany, Dr. Brian Ogilvie, Vice President of Scientific Consulting, presented a comparison...
Maximize Metabolic Activities by Limiting Hepatocyte Cryoinjury
Cryopreservation and thawing of primary hepatocytes causes inherent damage to the cells. Traditional pooling methods require cells to undergo two separate cryopreservation...
Assess Catabolic Stability of Biologics & ADCs with Lysosomes – Characterized Test Systems
Originally published in tebu-bio’s Being Bioreactive. To purchase XenoTech’s products in the EU, please visit tebu-bio’s website. Following up on my series...
No More Water Baths! Simplify Hepatocyte Thaws and Eliminate Contamination
XenoTech has patented technology that eliminates the need for the water baths that are traditionally required to thaw cryopreserved hepatocytes. By removing water...
XenoTech Adds US Support for MATE1 and MATE2-K Drug Transporter Studies
Transporters have become increasingly important in drug development due to the major role they play in absorption, distribution and excretion of...
XenoTech Named Best In Vitro Drug Metabolism Studies Provider 2018
Following our nomination in late 2017, XenoTech has been named the Best In Vitro Drug Metabolism Studies Provider in the...
Choosing a Relevant Small Animal Model for Pharmacokinetic or Toxicity Studies
Choosing the most suitable small animal model is crucial for pharmacokinetic and/or toxicology studies in order to get usable, relevant data. Due to potential...
Recombinant CYP Bactosomes: Versatile Formats for Many ADME Applications
Originally published in tebu-bio’s Being Bioreactive. To purchase recombinant CYPs in the EU, please visit tebu-bio’s website. For North American orders, please follow...
Insects and Cattle and Sheep, Oh My!
Over the past two decades, we’ve received a lot of interesting requests for custom tissue preparations here at XenoTech. “We’ve...
XenoTech Hiring and Growing to Meet Customer Demand
As announced earlier this month, XenoTech has hired a record number of new staff over the past year in order to...
Subscribe to our Newsletter
Stay up to date with our news, events and research
Do you have a question or a request for upcoming blog content?
We love to get your feedback
