2018 | Page 2 of 3

Response to FDA Framework for Assessment of Drug-Drug Interactions for Therapeutic Proteins RFI and Comments

In July, Drs. Maciej Czerwinski, Director of Consulting, and Brian Ogilvie, Vice President of Scientific Consulting, submitted XenoTech’s comments in response to the Food...

IQ Induction Working Group Publishes Recommendations for Data Interpretation of In Vitro Induction – Focus on CYP3A4 mRNA

XenoTech is proud to have made contributions to the paper entitled, “Considerations from the IQ Induction Working Group in Response...

New Guidance on Bioanalytical Services

XenoTech offers bioanalytical services to support both internal groups and external clients. We have validated LC-MS/MS methods for human CYP markers, UDP...

No-Cost, On-Demand Primary Human Hepatocyte Pooling Using CryostaX Pellets

CryostaX® hepatocytes are created using a patented process that produces unique single-donor cell pellets. This format allows scientists to easily pool primary...

NADPH RapidStart Regeneration System for Extended Metabolism

Originally published in tebu-bio’s Being Bioreactive. To purchase XenoTech’s products in the EU, please visit tebu-bio’s website. NADPH is a critical cofactor...

AAPS-FDA Drug Transporters

The American Association of Pharmaceutical Scientists (AAPS) and U.S. Food and Drug Administration (FDA) co-sponsored the workshop “Drug Transporters in ADME:...

In Vitro DDI Regulatory Guidance Reference Poster

At the 2018 Marbach Castle Drug-Drug Interaction Workshop in Germany, Dr. Brian Ogilvie, Vice President of Scientific Consulting, presented a comparison...

Maximize Metabolic Activities by Limiting Hepatocyte Cryoinjury

Cryopreservation and thawing of primary hepatocytes causes inherent damage to the cells. Traditional pooling methods require cells to undergo two separate cryopreservation...

Assess Catabolic Stability of Biologics & ADCs with Lysosomes – Characterized Test Systems

Originally published in tebu-bio’s Being Bioreactive. To purchase XenoTech’s products in the EU, please visit tebu-bio’s website. Following up on my series...

No More Water Baths! Simplify Hepatocyte Thaws and Eliminate Contamination

XenoTech has patented technology that eliminates the need for the water baths that are traditionally required to thaw cryopreserved hepatocytes. By removing water...

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Year: 2018