Commentary to provide context and explain significance of research is sometimes just as important as the research itself. That’s why our experts make it a priority to provide you with helpful content distilled from the many years of experience our team has accumulated. The Drug Development Insights blog contains overviews and deep dives into the drug metabolism and pharmacokinetics topics you care about—regulatory expectations, risk assessment, safety considerations, scientific innovation, study design elements, interpretation of results, and more. Explore our entries chronologically or by category to get insight into the many pieces of your drug’s development.
Drug Development Blog
Missing Out on Annual ‘Comforting of the Soul’
- Our Team
- May 29, 2020
- Deja Coffin, Madison Esely-Kohlman, Jolanta Golec
As we begin this summer, many of us are grieving opportunities lost for parties and pool days with friends and...
What is DMPK and how does it fit into drug development?
- Drug Metabolism
- May 11, 2020
- Madison Esely-Kohlman
Drug metabolism and pharmacokinetics (DMPK) is a core discipline in drug development that considers the biotransformation of a drug compound...
Meet the Scientist: Pallavi Limaye
- Meet the Scientist
- April 28, 2020
- Madison Esely-Kohlman
We have welcomed a new consultant to the team! Dr. Pallavi Limaye now serves as a Director in the Scientific...
ADME and Drug-Drug Interactions for the Toxicologist
- Drug Drug Interactions (DDI)
- April 28, 2020
- Madison Esely-Kohlman
Highlights from the recent webinar presented by our newest expert consultant, Dr. Pallavi Limaye In her recent webinar (now available for...
New TMPRSS2-Expressing Cell Line for COVID-19 Research
- Updated Offerings
- April 23, 2020
- Madison Esely-Kohlman
We are offering a brand new cell line to assist researchers in the fight against COVID-19.The cell line (JCRB1819), developed...
What is ADME and how does it fit into drug development?
- Drug Metabolism
- April 10, 2020
- Madison Esely-Kohlman, Dr. Brian Ogilvie
The main aim of drug development is to get a compound that has a therapeutic effect into the form of...
COVID-19 Updates
- Drug Drug Interactions (DDI)
- March 25, 2020
- Michael Millhollen
As a global Life Sciences and Healthcare company, XenoTech recognizes the seriousness of the Coronavirus Pandemic. We are constantly monitoring...
In Vitro Evaluation of Drug-Drug Interaction (DDI) Potential
- Enzyme Inhibition
- March 24, 2020
- Madison Esely-Kohlman, Zachary Mitts, Dr. Joanna Barbara
In its most recent in vitro drug interaction guidance update, the US Food and Drug Administration (FDA) emphasized harmony with the...
Four ways to optimize preclinical in vitro data to mitigate risk of late-stage clinical failure
- Consultancy
- March 9, 2020
- Madison Esely-Kohlman
1. Collect high-quality data to make informed, confident go/no go decisions for moving your drug candidate forward If you need...
How can in vitro and in vivo studies help me understand my drug’s clearance?
- Regulatory Guidance
- March 5, 2020
- Madison Esely-Kohlman, Dr. Joanna Barbara
Systemic clearance, denoting how much drug is cleared from a volume of blood per unit of time, is of critical...
Subscribe to our Newsletter
Stay up to date with our news, events and research
Do you have a question or a request for upcoming blog content?
We love to get your feedback