Fresh human hepatocytes are available in suspension or plated on collagen-coated plates and offer an alternative to in vivo or cryopreserved hepatocytes. Hepatocyte preparations are delivered in vial format for suspension or on collagen-coated plates with a Matrigel overlay for plated/attaching cells.
Fresh Primary Human Hepatocytes
Available Formats for Fresh Primary Human Hepatocytes
Because of the time-sensitive nature of fresh human hepatocyte products, we only offer them when human donor tissue is received; however, fresh animal hepatocytes can be prepared upon request as a Custom Preparation.
| Enzyme | Marker Substrate Reaction | plated or Suspension |
|---|---|---|
| CYP1A2 | Phenacetin O-dealkylation | Plated |
| CYP2B6 | Bupropion hydroxylation | Plated |
| CYP3A4 | Midazolam 1′-hydroxylation | Plated |
| CYP | 7-Ethoxycoumarin O-dealkylation | Suspension |
| UGT | 7-Hydroxycoumarin glucuronidation | Suspension |
| SULT | 7-Hydroxycoumarin sulfonation | Suspension |
*Includes Isolation Viability
Be Prepared
Download a thorough guide put together by our in-house specialists to help you make the most of your fresh human hepatocytes.
