P450 Substrates and Metabolites

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Sekisui XenoTech is the exclusive North American distributor of Cypex’s wide range of cytochrome P450 substrates and metabolites. Substrates and their corresponding metabolites are commonly used in early-stage drug discovery services. These substrates can identify a compound’s ability to prevent the production of specific metabolites to help you expedite drug candidate selection.

Sekisui XenoTech offers an extensive list of cytochrome P450 substrates and metabolites, some of which are radiolabeled to ease detection. They are supplied at high purity and in convenient package sizes to easily meet the unique needs of any study.

Contact a Product Specialist for more information on cytochrome P450 substrate and metabolite products
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Product Description Volume
CYP500 4-hydroxydiclofenac, 0.1mg 0.1mg
CYP500-5 4-hydroxydiclofenac, 5 mg 5MG
CYP501 6alpha-hydroxypaclitaxel, 0.1mg 0.1mg
CYP501-5 6alpha-hydroxypaclitaxel, 5.0 mg 5MG
CYP502 [1-14C]-Lauric acid, 50 µCi 50 uCi
CYP503 [1-14C]-11-hydroxylauric acid, 50 µCi 50 uCi
CYP504 [1-14C]-12-hydroxylauric acid, 50 µCi 50 uCi
CYP505 Tolbutamide, 100 mg 100 mg
CYP506 Hydroxytolbutamide, 10 mg 10 mg
CYP507 Carboxytolbutamide, 10 mg 10 mg
CYP508 Carboxytolbutamide methyl ester, 10 mg 10 mg
CYP509 Tolbutamide Kit (CYP505-508) Each
CYP510 7-ethoxyresorufin, 10 mg 10 mg
CYP511 Resorufin, 100 mg 100 mg
CYP512 7-benzyloxyquinoline, 10 mg 10 mg
CYP513 7-hydroxyquinoline, 10 mg 10 mg
CYP514 [14C] 7-ethoxycoumarin, 50 µCi 50 uCi
CYP515-10 MAMC, 10mg 10 mg
CYP515-25 MAMC, 25mg 25 mg
CYP516 HAMC, 10mg 10 mg
CYP517-10 7-methoxy-4-trifluoromethylcoumarin (MFC), 10mg 10 mg
CYP517-25 7-methoxy-4-trifluoromethylcoumarin (MFC), 25 mg 25 mg
CYP519 7-hydroxy-4-trifluoromethylcoumarin (HFC), 10mg 10 mg
CYP520 Omeprazole, 1g Each
CYP521-10 3-O-methylfluorescein, 10 mg 10 mg
CYP521-25 3-O-methylfluorescein, 25mg 25 mg
CYP522-10 Tienilic Acid, 10mg 10 mg
CYP522-25 Tienilic Acid, 25mg 25 mg
CYP523-100 Paclitaxel, 100 mg 100 mg
CYP523-25 Paclitaxel, 25 mg 25 mg
CYP524-100 Ketoconazole, 100 mg 100 mg
CYP524-1000 Ketoconazole, 1 g 1 g
CYP525 Diclofenac, 10 g 10 g
CYP526 Amodiaquine, 5g 5 g
CYP527-10 Desethylamodiaquine, 10mg 10 mg
CYP527-25 Desethylamodiaquine, 25mg 25 mg
CYP528 Terfenadine, 5g 5 g
CYP529-10 R-(-)-N-benzylphenobarbital, 10 mg 10 mg
CYP529-25 R-(-)-N-benzylphenobarbital, 25 mg 25 mg
CYP530-10 Montelukast sodium, 10 mg 10 mg
CYP530-25 Montelukast sodium, 25 mg 25 mg
CYP531-10 Diethoxyfluorescein (DEF), 10 mg 10 mg
CYP531-25 Diethoxyfluorescein (DEF), 25 mg 25 mg
CYP532 S-mephenytoin, 5.0 mg 5MG
CYP533 (+/-)-4'hydroxymephenytoin, 5.0mg 5MG
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