Control cytochrome P450 (CYP) substrates and their corresponding metabolites are commonly used in early-stage drug discovery services to identify a compound’s ability to prevent the production of specific metabolites to help you expedite drug candidate selection. We are proud to be the exclusive North American distributor of a wide range of CYP substrates and metabolites from Cypex, a distinguished producer of recombinant drug-metabolizing enzymes for global pharma and agrochemical development.
Cytochrome P450 (CYP) Substrates & Metabolites in Preclinical Drug Development
Available Cytochrome P450 (CYP) Substrates and Metabolites
- 6alpha-hydroxypaclitaxel (0.1 mg)
- 6alpha-hydroxypaclitaxel (5.0 mg)
- Amodiaquine, 5g
- 7-benzyloxyquinoline, 10 mg
- Carboxytolbutamide, 10 mg
- Carboxytolbutamide methyl ester, 10 mg
- Desethylamodiaquine, 10mg
- Desethylamodiaquine, 25mg
- Diclofenac, 10 g
- Diethoxyfluorescein (DEF), 10 mg
- Diethoxyfluorescein (DEF), 25 mg
- 7-ethoxyresorufin, 10 mg
- [14C] 7-ethoxycoumarin, 50 µCi
- HAMC, 10mg
- 4-hydroxydiclofenac (0.1 mg)
- 4-hydroxydiclofenac (5 mg)
- [1-14C]-11-hydroxylauric acid (50 µCi)
- [1-14C]-12-hydroxylauric acid (50 µCi)
- (+/-)-4’hydroxymephenytoin, 5.0mg
- 7-hydroxyquinoline, 10 mg
- 7-hydroxy-4-trifluoromethylcoumarin (HFC), 10mg
- Hydroxytolbutamide, 10 mg
- Ketoconazole, 100 mg
- Ketoconazole, 1 g
- [1-14C]-Lauric acid (50 µCi)
- MAMC, 10mg
- MAMC, 25mg
- 7-methoxy-4-trifluoromethylcoumarin (MFC), 10mg
- 7-methoxy-4-trifluoromethylcoumarin (MFC), 25 mg
- Montelukast sodium, 10 mg
- Montelukast sodium, 25 mg
- Omeprazole, 1g
- 3-O-methylfluorescein, 10 mg
- 3-O-methylfluorescein, 25mg
- Paclitaxel, 25 mg
- Paclitaxel, 100 mg
- Resorufin, 100 mg
- R-(-)-N-benzylphenobarbital, 10 mg
- R-(-)-N-benzylphenobarbital, 25 mg
- S-mephenytoin, 5.0 mg
- Terfenadine, 5g
- Tienilic Acid, 10mg
- Tienilic Acid, 25mg
- Tolbutamide (100 mg)
- Tolbutamide Kit (CYP505-508)
Our offerings include an extensive list of Cytochrome P450 (CYP) substrates and metabolites, some of which are radiolabeled to ease detection. They are supplied at high purity and in convenient package sizes to easily meet the unique needs of any study.