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Liver fibrosis, fat, steatosis, steatohepatitis, ballooned hepatocytes, etc. tissue samplesOur Research BioBank is committed to providing normal and diseased human tissue samples for scientific investigation at a reasonable cost. We currently offer liver and gallbladder tissue, which is collected with the initial intent for transplant, thus making it a perfect candidate to advance basic medical science and contribute to the development of new treatments. 

What is Sekisui XenoTech’s Research Biobank?

With this initiative, we are providing the research community with a collection of high-quality human liver tissue specimens and arrays representing the early stages of alcoholic or non-alcoholic fatty liver disease. Human gallbladder tissue is also available, usually from matching donors. The samples being assembled are available in quantities larger than those obtained during needle biopsies and come from organs initially intended for transplantation. Our tissue specimens are collected in a timely manner with precise care taken to minimize downtime and preserve tissue viability. These circumstances of tissue harvest distinguish our Biobank from human tissue samples collected in a typical post-mortem, usually associated with several hours of a warm ischemia.

H&E slides are prepared for each lot to illustrate tissue conditions and, together with the patient’s medical history, to offer a basic diagnosis. Masson’s trichrome slides are prepared as justified to establish the presence or absence of liver fibrosis.

Why use Sekisui XenoTech’s tissue samples?

The tissue samples and microarrays in Sekisui XenoTech’s Research Biobank allow for the analysis of expression of drug targets and early markers of fatty liver diseases across diverse populations of US transplant liver donors (click here to view NASH donors). Tissue samples and tissue arrays come with pathologic diagnosis, demographic, BMI, history of diabetes and alcohol use data. Representative microphotographs are also available for each specimen. A selection of normal tissues is collected to satisfy requirements of a control population. A separate category of pediatric donors, age 1 month to 11 years old, is available for specialized investigations in this age group.

Download a list of donors available in the Research Biobank

Liver and Gallbladder Tissue, Hepatocytes, Subcellular Fractions, Paraffin Block Slides and Microarrays

Liver tissue samples, gallbladder tissue samples or arrays and other preparations may be purchased using the links below. Disease-defined hepatocytes have been prepared from certain donors (healthy and those with early stages of alcoholic or non-alcoholic fatty liver disease or diabetes, see donor list for availability). Additionally, a pool of human liver microsomes and S9 from NASH donors has already been prepared. These test systems have the potential to be a convenient human model of the aforementioned diseases. They are offered to scientists interested in disease biomarkers, in vivo / in vitro correlation of disease biomarker expression, with the aim of advancing in vitro studies of ailments linked to obesity and alcohol consumption. Subcellular fractions and paraffin block slides can also be prepared upon request from many of the donors.

Donors that have already had hepatocyte isolations prepared for sale are highlighted in green in the following spreadsheet:

View a list with many of the donors available in the Research Biobank
or place an order using the options below:

Buy cell and tissue based products

View NASH Donor Pool of Human Liver Microsomes or S9

View Liver Disease Tissue Microarrays

Or Request Tissue Specimens, Hepatocytes, Subcellular Fractions, Paraffin Block Slides:

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